Synchronous primary cancers in a woman with scleroderma: a case report
| Main Authors: | Androutsopoulos Georgios, Adonakis Georgios, Tsamantas Athanasios, Liosis Stamatis, Antonopoulos Andreas, Kourounis Georgios |
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| Format: | Article Journal |
| Bahasa: | eng |
| Terbitan: |
, 2008
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/6027628 |
Daftar Isi:
- Background: Scleroderma is a chronic, multisystem, autoimmune disease. Previous studies have shown an increased risk of malignancy in scleroderma. The most common cancers were lung cancer and breast cancer. Case: The patient, a 43-year-old nulliparous premenopausal Greek woman suffering of scleroderma, presented with a history of abdominal pain and atypical vaginal bleeding. She underwent total hysterectomy with bilateral salpingo-oophorectomy, total omentectomy, appendectomy and pelvic lymph node dissection. The histopathology revealed synchronous primary cancers of the endometrium and left ovary. She underwent to postoperative chemotherapy and remains well without evidence of disease 25 months after operation. Conclusion: Synchronous primary cancers of the endometrium and ovary are relatively uncommon in general population. Only few cases of cancer of the female genital tract in women with scleroderma have been reported in the English literature.