Primary malignant melanoma of the vagina: a case report

Main Authors: Androutsopoulos Georgios, Adonakis Georgios, Ravazoula Panagiota, Kourounis Georgios
Format: Article Journal
Bahasa: eng
Terbitan: , 2005
Subjects:
Online Access: https://zenodo.org/record/6014155
Daftar Isi:
  • Primary malignant melanoma of vagina is a very rare, but very aggressive tumor. We describe a case of primary vaginal melanoma and review the literature. The patient, a 73-year-old, gravida 2, para 2 postmenopausal Greek woman, presented abnormal vaginal bleeding for 30 days. On vaginal examination there was a 5.5 x 5 x 2 cm raised, ulcerated and irregular lesion of posterior vaginal wall. Pathology examination of the entire specimen demonstrated a nodular vaginal melanoma. The histologic diagnosis was confirmed by positive immunostaining. The patient began postoperative immunotherapy with interferon-a2b. She died 25 months later because of cerebral metastases. In conclusion, the prognosis of vaginal melanoma is very poor, despite the treatment modality, because most of cases were diagnosed at a late stage.