Analysis on Soy-Yamgurt Potential as Antidiabetic in Streptozotocin-Nicotinamide Induced Rats

Main Authors: Kwanariesta, Jessica, Rusmarilin, Herla, Suhaidi, Ismed
Format: Article info application/pdf eJournal
Bahasa: eng
Terbitan: Talenta Publisher , 2018
Subjects:
Online Access: https://talenta.usu.ac.id/InJAR/article/view/174
https://talenta.usu.ac.id/InJAR/article/view/174/129
ctrlnum article-174
fullrecord <?xml version="1.0"?> <dc schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"><title lang="en-US">Analysis on Soy-Yamgurt Potential as Antidiabetic in Streptozotocin-Nicotinamide Induced Rats</title><creator>Kwanariesta, Jessica</creator><creator>Rusmarilin, Herla</creator><creator>Suhaidi, Ismed</creator><subject lang="en-US">antioxidant activity, diabetes mellitus, soy milk, soy-yamgurt, streptozotocin-nicotinamide</subject><description lang="en-US">This study was conducted to determine the potential of soy-yamgurt probiotics drink from the mixture of yam and soy extract with a ratio of 1: 1 in reducing the fasting blood glucose level of rats induced by streptozotocin-nicotinamide. Based on the analysis of chemical and phytochemical characteristics of soy-yamgurt, it was found that it has water content (80.97%), total solids (18.85%), protein content (11.95%), total lactic acid (1.03%), viscosity (20.56 Pa.s), lactic acid bacteria (10.22 log CFU/g), fiber content (0.98%), IC50 value (44.99 &#x3BC;g/ml), total phenol (711.90 &#x3BC;gGAE/g) and total flavonoids (1345.73 &#x3BC;gQE/g). The in vivo test used thirty 10-16 week old male Wistar rats with an average weight of 160-200 g divided into 5 groups: P1 (control), P2 (streptozotocin-nicotinamide), P3 (glibenclamide of 0.45 mg/kg body weight), P4 (3 ml of soy-yamgurt) and P5 (3.5 ml of soy-yamgurt).The results showed that the soy-yamgurt at the doses of 3 ml/160 g body weight and 3.5 ml/160 g body weight for 4 weeks in streptozotocin-nicotinamide-induced rats had significantly (P&amp;lt;0.01) lowered blood glucose levels and increased their weight.</description><publisher lang="en-US">Talenta Publisher</publisher><date>2018-03-31</date><type>Journal:Article</type><type>Other:info:eu-repo/semantics/publishedVersion</type><type>Journal:Article</type><type>File:application/pdf</type><identifier>https://talenta.usu.ac.id/InJAR/article/view/174</identifier><identifier>10.32734/injar.v1i1.174</identifier><source lang="en-US">Indonesian Journal of Agricultural Research; Vol 1 No 1 (2018): InJAR, Vol. 1, No. 1, March 2018; 58-70</source><source>2615-5842</source><source>2622-7681</source><language>eng</language><relation>https://talenta.usu.ac.id/InJAR/article/view/174/129</relation><rights lang="en-US">Copyright (c) 2018 Indonesian Journal of Agricultural Research</rights><recordID>article-174</recordID></dc>
language eng
format Journal:Article
Journal
Other:info:eu-repo/semantics/publishedVersion
Other
File:application/pdf
File
Journal:eJournal
author Kwanariesta, Jessica
Rusmarilin, Herla
Suhaidi, Ismed
title Analysis on Soy-Yamgurt Potential as Antidiabetic in Streptozotocin-Nicotinamide Induced Rats
publisher Talenta Publisher
publishDate 2018
topic antioxidant activity
diabetes mellitus
soy milk
soy-yamgurt
streptozotocin-nicotinamide
url https://talenta.usu.ac.id/InJAR/article/view/174
https://talenta.usu.ac.id/InJAR/article/view/174/129
contents This study was conducted to determine the potential of soy-yamgurt probiotics drink from the mixture of yam and soy extract with a ratio of 1: 1 in reducing the fasting blood glucose level of rats induced by streptozotocin-nicotinamide. Based on the analysis of chemical and phytochemical characteristics of soy-yamgurt, it was found that it has water content (80.97%), total solids (18.85%), protein content (11.95%), total lactic acid (1.03%), viscosity (20.56 Pa.s), lactic acid bacteria (10.22 log CFU/g), fiber content (0.98%), IC50 value (44.99 μg/ml), total phenol (711.90 μgGAE/g) and total flavonoids (1345.73 μgQE/g). The in vivo test used thirty 10-16 week old male Wistar rats with an average weight of 160-200 g divided into 5 groups: P1 (control), P2 (streptozotocin-nicotinamide), P3 (glibenclamide of 0.45 mg/kg body weight), P4 (3 ml of soy-yamgurt) and P5 (3.5 ml of soy-yamgurt).The results showed that the soy-yamgurt at the doses of 3 ml/160 g body weight and 3.5 ml/160 g body weight for 4 weeks in streptozotocin-nicotinamide-induced rats had significantly (P&lt;0.01) lowered blood glucose levels and increased their weight.
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institution Universitas Sumatera Utara
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Animal Science and Fisheries
Agribusiness
Bioscience
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