PENGARUH PEMBERIAN MADU SEBAGAI ANTIOKSIDAN TERHADAP DIAMETER ALVEOLI PARU TIKUS (Rattus novergicus) YANG DIPAPAR ASAP ROKOK SECARA SUB AKUT
| Main Author: | Ul Khasanah, Nidha |
|---|---|
| Format: | Thesis NonPeerReviewed Book |
| Bahasa: | eng |
| Terbitan: |
, 2008
|
| Subjects: | |
| Online Access: |
http://eprints.umm.ac.id/6810/1/PENGARUH_PEMBERIAN_MADU_SEBAGAI_ANTIOKSIDAN_TERHADAP_DIAMETER_ALVEOLI_PARU_TIKUS.pdf http://eprints.umm.ac.id/6810/ |
| ctrlnum |
6810 |
|---|---|
| fullrecord |
<?xml version="1.0"?>
<dc schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"><relation>http://eprints.umm.ac.id/6810/</relation><title>PENGARUH PEMBERIAN MADU SEBAGAI ANTIOKSIDAN TERHADAP 
DIAMETER ALVEOLI PARU TIKUS (Rattus novergicus) YANG DIPAPAR 
ASAP ROKOK SECARA SUB AKUT</title><creator>Ul Khasanah, Nidha</creator><subject>R Medicine (General)</subject><description>Cigarette smoke contains abundant free radical molecules. The free radical molecules either of cigarette smokes may inactivate α1­anti trypsin. So elastase is insufficiently inhibited by α1­anti trypsin and elastase degraded elastic fibre which responsible for the elasticity of lung and 
airways. Therefore, the influence of various dosage of honey, an antioxidant on alveolar diameter of rat lung with sub acute method that exposed by cigarette smoke were investigated. 
This research made use 25 healthy male wistar rats, were randomly grouped into 5 groups of 5 each. Group I is the controlled group, group II is the group exposed to cigarette smoke for 10 weeks. Group III, IV, and V are the group exposed both to cigarette smoke and 3 dosage of 
honey (1.6, 1.8, and 2 ml/day). 10 weeks later the lung tissues were stained by HE. The diameters of alveoli were observed under microscope and measured using micrometer. 
The result shows that there are enlargement of alveolar diameter caused by cigarette smoke with sub acute method and honey may reduce the enlargement of alveolar diameter caused by cigarette smoke. The optimum dose of honey is 1.8 ml/day. When dosage of honey increased to 2 ml/day then effect were reduced. This phenomenon may be caused by pro oxidant effect of vitamin C and vitamin D on honey.</description><date>2008</date><type>Thesis:Thesis</type><type>PeerReview:NonPeerReviewed</type><type>Book:Book</type><language>eng</language><identifier>http://eprints.umm.ac.id/6810/1/PENGARUH_PEMBERIAN_MADU_SEBAGAI_ANTIOKSIDAN_TERHADAP_DIAMETER_ALVEOLI_PARU_TIKUS.pdf</identifier><identifier> Ul Khasanah, Nidha (2008) PENGARUH PEMBERIAN MADU SEBAGAI ANTIOKSIDAN TERHADAP DIAMETER ALVEOLI PARU TIKUS (Rattus novergicus) YANG DIPAPAR ASAP ROKOK SECARA SUB AKUT. Other thesis, University of Muhammadiyah Malang. </identifier><recordID>6810</recordID></dc>
|
| language |
eng |
| format |
Thesis:Thesis Thesis PeerReview:NonPeerReviewed PeerReview Book:Book Book |
| author |
Ul Khasanah, Nidha |
| title |
PENGARUH PEMBERIAN MADU SEBAGAI ANTIOKSIDAN TERHADAP
DIAMETER ALVEOLI PARU TIKUS (Rattus novergicus) YANG DIPAPAR
ASAP ROKOK SECARA SUB AKUT |
| publishDate |
2008 |
| topic |
R Medicine (General) |
| url |
http://eprints.umm.ac.id/6810/1/PENGARUH_PEMBERIAN_MADU_SEBAGAI_ANTIOKSIDAN_TERHADAP_DIAMETER_ALVEOLI_PARU_TIKUS.pdf http://eprints.umm.ac.id/6810/ |
| contents |
Cigarette smoke contains abundant free radical molecules. The free radical molecules either of cigarette smokes may inactivate α1anti trypsin. So elastase is insufficiently inhibited by α1anti trypsin and elastase degraded elastic fibre which responsible for the elasticity of lung and
airways. Therefore, the influence of various dosage of honey, an antioxidant on alveolar diameter of rat lung with sub acute method that exposed by cigarette smoke were investigated.
This research made use 25 healthy male wistar rats, were randomly grouped into 5 groups of 5 each. Group I is the controlled group, group II is the group exposed to cigarette smoke for 10 weeks. Group III, IV, and V are the group exposed both to cigarette smoke and 3 dosage of
honey (1.6, 1.8, and 2 ml/day). 10 weeks later the lung tissues were stained by HE. The diameters of alveoli were observed under microscope and measured using micrometer.
The result shows that there are enlargement of alveolar diameter caused by cigarette smoke with sub acute method and honey may reduce the enlargement of alveolar diameter caused by cigarette smoke. The optimum dose of honey is 1.8 ml/day. When dosage of honey increased to 2 ml/day then effect were reduced. This phenomenon may be caused by pro oxidant effect of vitamin C and vitamin D on honey. |
| id |
IOS4109.6810 |
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Universitas Muhammadiyah Malang |
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136 |
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library:university library |
| library |
Perpustakaan Universitas Muhammadiyah Malang |
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546 |
| collection |
UMM Institutional Repository |
| repository_id |
4109 |
| city |
MALANG |
| province |
JAWA TIMUR |
| repoId |
IOS4109 |
| first_indexed |
2017-03-21T02:40:34Z |
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2017-03-21T02:40:34Z |
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dc |
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1675924128777895936 |
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17.538404 |