PENGARUH KONSUMSI SUPLEMEN EKSTRAK KULIT MANGGIS (Garcinia mangostana L.) TERHADAP INFLAMASI GINGIVA PADA PASIEN ORTODONTIK CEKAT (Kajian Jumlah Leukosit Cairan Sulkus Gingiva)
| Main Authors: | , ANGGY NATYA LISTYANINGRUM, , drg. Prayitno, SU. |
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| Format: | Thesis NonPeerReviewed |
| Terbitan: |
[Yogyakarta] : Universitas Gadjah Mada
, 2014
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| Subjects: | |
| Online Access: |
https://repository.ugm.ac.id/132406/ http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=72939 |
Daftar Isi:
- Gingival inflammation is a clinical sign of periodontal disease characterized by increasing number of leukocytes GCF which produce cytokines that capable to destruction of the host tissue. Fixed orthodontic appliance user had a greater tendency towards the occurrence of gingival inflammation. The mangosteen pericarps (Garcinia mangostana L.) containsxantonewhich have antiinflammatory activity. The purpose of this study was todetermine the effect of consumingmangosteen pericarps extract supplement (Garcinia mangostana L.) to reduce gingival inflammation index in fixedorthodontic patient with number of leukocyte GCF count. Twenty subjects of fixed orthodontic patient were then divided into two groups: 10 subjects in the treatment group and 10 subjects in the control groupwereselected based on the criteria of inclusion: age 18-24 years old, was have gingival inflammation from mild to moderate, use fixed orthodontic appliance on the finishing phase. Subjects in both groups were given an initial therapy (scaling), then the treatment group consumed mangosteen pericarp extract supplements with a frequency of 3 times of 2 capsules for 7 days. Sampling GCF in both groups were did on day 0 and day 8 on regio anterior lower as much as 3 sample GCF of each subject. Leukocytes was seen from the sample with a reagent staining results Turk through the microscope with a magnification of 400 times. The mean reduction number of leukocytes was analyzed usingthe Independent TTest. The results showed that the effect of consumingmangosteen pericarp extract supplements (Garciniamangostana L.) towards a decrease in the number of leukocytes GCF was significant (p<0,05).The conclusions of this research was consumption mangosteen pericarps extract supplement (Garcinia mangostana L.) effect significantly to decrease the inflammation of the gingiva at the fixed orthodontic patient as seen from reducesthe number of leukocytes GCF