Vaginal primary malignant melanoma: a critical update

Main Authors: Androutsopoulos Georgios, Decavalas Georgios
Format: Article Journal
Bahasa: eng
Terbitan: , 2014
Subjects:
Online Access: https://zenodo.org/record/6060404
Daftar Isi:
  • Vaginal primary malignant melanoma (VPMM) is a rare and very aggressive tumor. The estimated incidence of VPMM is 0.026/100,000 women per year. The mean age at diagnosis is 57 years. The most common symptoms and signs are: vaginal bleeding (80%), vaginal discharge (25%), palpable vaginal mass (15%) and pain (10%). Although there are several treatment options for patients with VPMM, an appropriate and effective treatment protocol has not defined yet. Surgery remains the primary treatment of choice in patients with VPMM. The spectrum of surgery ranges from conservative (wide local excision) to radical (vaginectomy, pelvic exenteration). It is obvious that the prognosis of VPMM is very poor despite treatment modality, as most cases diagnosed at advanced stage.