Piper cubeba 2 4-Diaminoquinazoline Dioxygenase Acyclovir Anti-Inflammatory Agents Antibacterial Agents Antioxidant activity Bacteriocin Cloud Software-as-a-Service (SaaS) Cloud computing Compound Sturcture Computation Independent Model (CIM) DPPH DoE Escherichia coli Microsponge Model Transformation Model-Driven Architecture (MDA) Phytochemical Piper nigrum Platform Independent Model (PIM) Platform Specific Model (PSM) QbD Quinazolinone derivatives Tuberculosis Mycobacterium tuberculosis Antibacterial activity UN UNdata datasets plant extract