EFEKTIVITAS ANTIBAKTERI EKSTRAK BUAH PALA (Myristica fragrans) DALAM MENGHAMBAT PERTUMBUHAN BAKTERI Streptococcus viridans (In vitro)
Daftar Isi:
- Antibacterial is a substance that can disturb growth or killed activitybacteria. Nutmeg is one of the natural substances that have antibacterial.Bioactive compounds in nutmeg are antibacterial essential oils, saponins, andalkaloids. The aim of this study was to determine the effectiveness of antibacterialextracts of nutmeg (Myristica fragrans) in inhibiting the growth of Streptococcusviridans. This research used quasi experimental with post test only control groupdesign. Aquades was used as negative control group; chlorhexidine 2% was usedas positive control group; the treatment group used nutmeg extract withconcentrations of 4%, 8%, 12%, and 16%, respectively. Extracts obtained bymaceration method. Antibacterial activity testing using agar diffusion (Kirby-Baurer Discs) with Shapiro-Wilk test data analysis, Levene-Test, one way ANOVAtest, and Post-Hoc Test. The result showed that nutmeg extract has antibacterialeffect on the Streptococcus viridans with the most inhibitory zone, at 16%concentration (8,34 mm), while in the positive control the inhibition zone was(17.26 mm). This study concluded that nutmeg extract at a concentration of 4%,8%, 12%, 16% has antibacterial effect in inhibiting the growth of Streptococcusviridans, but not as effective as chlorhexidine 2%.