KORELASI SKOR APRI (AST to Platelet Ratio Index) DENGAN KADAR ALBUMIN SERUM PADA PENDERITA SIROSIS HATI DI RSUP DR MOHAMMAD HOESIN PALEMBANG
Daftar Isi:
- Background: Cirrhosis is the final stage of progressive liver fibrosis diffused process which is characterized by distortion of liver architecture and formation of degenerative nodul. The disease will decrease hepatocellular function which is hypoalbumin. Cirrhosis can be diagnosed by APRI score which is an alternative to liver biopsy. This study is intended to determine the corelation between serum albumin level with APRI score amongst cirrhosis patients. Method: The study was an analytic observasional study with cross sectional design that used medical record data at RSUP Dr. Mohammad Hoesin Palembang year 2015-2016. Subjects of the study were hospitalized cirrhosis patients and were taken with total sampling technique. Data were analyzed by Pearson test. Result: From 31 samples, there were 22 male subjects (71%) and 9 female subjects (29%). The most age was in 51-57 years old (51,6%). Most of the subjects had recent high school education (74.2%) and worked as farmer (29%). Ascites were present in most subjects (58.1%). The mean hemoglobin value of the subjects showed anemia (10.5 ± 2.16 g/dL) and most of the subjects had thrombocytopenia (74.2%). Many subjects had elevated serum AST levels (77.4%) and serum ALT levels (74.2%). Most of the subjects experienced hypoalbumin (83,9%) and hyperglobulin (61.3%). APRI score data more at values over 1.5, indicating liver cirrhosis. There was no correlation between APRI scores with serum albumin levels (p=0.889) Conclusion: There is no corelation between APRI score with serum albumin level amongst cirrhosis patients.