ANALISIS EFEKTIVITAS PROGRAM IMUNISASI HEPATITIS B IMUNOGLOBULIN (HBIg) DALAM PENCEGAHAN PENULARAN DARI IBU KE ANAK DI KOTA PANGKALPINANG
Daftar Isi:
- Transmission of Hepatitis B from Mother to Child causes 90% of chronic Hepatitis B, liver cancer and death in children. For this reason, a Prevention of Hepatitis B from Mother to Child Transmission (MTCT) program is carried out by administering vaccines and immunoglobulins (HBIg) to infants immediately after birth. This study aimed to analyze the effectiveness of the HBIg administration program in preventing transmission of Hepatitis B from mother to child. This research was a descriptive analytic study with cross sectional approach. The study sample was 59 children aged > 1 year who were born by mothers with positive HBsAg. Samples were taken consecutively from the recipient of HBIg data from the Health Office of Pangkal Pinang. The effectiveness of HBIg is measured by HBsAg and Anti-HBs examination of children using the Rapid Diagnostic Test (RDT). The results obtained by the effectiveness of HBIg in preventing transmission of Hepatitis B by 98.3%. While the effectiveness of HBIg in causing antibodies or immunity is 49.2%. Based on the results of the chi-square test there is a significant relationship between the age of the child (p-value = 0.013), the time of HBIg administration (p-value = 0.007) and the completeness of immunization status (p-value = 0.026) and the effectiveness of HBIg. It can be concluded that administration of HBIg is effective in preventing transmission of Hepatitis B from Mother to Child. It is recommended to the Department of Health to improve coordination with hospitals so that HBIg is given less than 12 hours from birth and is equipped with a complete Hepatitis B vaccine so that the child has antibodies or immunity.