FAKTOR RISIKO PATEN DUKTUS ARTERIOSUS PADA PASIEN YANG DIRAWAT DI BAGIAN ANAK RSUP DR. MOHAMMAD HOESIN PALEMBANG PERIODE 1 JANUARI 2014-30 JUNI 2017
Daftar Isi:
- Background: In “term infants,” PDA occurs in 0.3-4/1000 live births at the end of the neonatal period, representing 5-10% of the congenital heart defects. In term infants, the ductus arteriosus normally constricts after birth and becomes functionally closed by 72 hours of age. Closure of the ductus occurs within hours in the majority (>95%) of term infants ≥37 weeks of gestation. In contrast, a persistent PDA, defined as failure of the ductus to close within 72 hours postnatal age, is seen in50% of very preterm infants born at <32 weeks of gestation. In premature infants, PDA incidence is inversely associated with gestational age (GA) and birth weight (BW). Methods: This research is an observational analytic study using cross sectional design and the data retrieval technique is done by purposive sampling. The data of this study were obtained from medical record of 26 infant patients suffering from PDA and 52 normal neonates who did not suffer PDA in medical record department of Dr. Mohammad Hoesin Palembang. The results were analyzed using Chi-square Test and Binary Logistic Regression Test using backward stepwise method. Results: Patients with PDA (33,3%),age 28 days-1 year (57,7%), male gender (53,8%), full terms (73,1%), normal birth weight (80,8%), not infected by rubella infection (80,8%), and no family history with PDA (100%). Using bivariate analysis showed that there was no significant relationship between gender and birth weight with PDA in RSMH Palembang (p=0,749 and p=0,231). There was a significant relationship between gestational age and rubella infection with PDA in RSMH Palembang (p=0.008 and (p=0.001). Using multivariate analysis showed that the most influential variables with PDA were gestational age (=0.015, OR=6.018). Conclusion: Gestational age is the most influential factor in the incidence of patent ductus arteriosus (PDA) in patients treated at the Pediatric Department of RSUP Dr. Mohammad Hoesin Palembang period January 1st 2014-June 30th 2017