KORELASI KADAR PROTEIN SERUM DAN DERAJAT KEGANASAN PADA PASIEN KANKER PARU DI RSUP DR MOHAMMAD HOESIN PALEMBANG
Daftar Isi:
- Background: Lung cancer is the highest cause of mortality in the world. In lung cancer there is an inhibition of albumin synthesis, that also affects globulin and total protein levels. The purpose of this study was to determine correlation of serum protein level and stage of malignancy in lung cancer patient at RSUP dr. Mohammad Hoesin Palembang. Methods: This study used an observational analytic study with cross sectional design conducted in November 2017. The study population was all lung cancer patients who were hospitalized in RSUP dr. Mohammad Hoesin Palembang. The sample of the study was cancer patients who were hospitalized at RSUP dr. Mohammad Hoesin Palembang during the period January 1, 2016 until July 31, 2017 that met inclusion criteria. Sampling was done by consecutive sampling. Data obtained from the installation of medical records RSUP dr. Mohammad Hoesin Palembang. The results obtained were analyzed by Spearman's statistical test. Results: Based on the results of the study, 96% of lung cancer patients in advanced stage and 4% in the early stages. In statistical test showed there was a significant correlation between albumin (p=0,021) and total protein (p=0,042) with malignancy degree in lung cancer patients. The correlation value of albumin (r=-0.230) and total protein (r=-0.204) was negative with weak correlation. Conclusion: There is correlation of albumin and total protein levels with degree of malignancy in lung cancer patients.