HUBUNGAN USIA DAN JENIS KELAMIN DENGAN DERAJAT DIFERENSIASI MENINGIOMA BERDASARKAN PEMERIKSAAN HISTOPATOLOGI
Daftar Isi:
- Backgroud. Meningioma is a predominantly benign and slow-growing neoplasm which is derived from meningothelial cells. The risk factors of meningioma that are known to have significant impacts are age and sex. Differentiation degree of meningioma can be determined by histophatological examination, and divided into WHO grade I, II, and II. This study was aimed to determine the association between age and sex with differentiation degree in meningioma based on histopathological examination. Method. A case series design was obtained in total of 90 samples from medical records at Department of Anatomical Pathology RSUP Dr. Mohammad Hoesin Palembang during the period 2014-2016. Spearman correlation analysis was used to determine the association between variables with correlation coefficient r ≥ 0,8. All data was processed by using SPSS. Results. The majority of meningioma cases were found in the age range of ≥40 years age (75,6%). Meningioma was more dominant in females compared to males (4:1) with WHO grade I as the most frequent one (84,4%). In this study, there was a significant and strong correlation between age and differentiation degree (p=0,000; r=0,612), along with sex and differentiation degree (p=0,000; r=0,705). Conclusion. There was a significant and strong correlation between age and sex with differentiation degree of meningioma.