Alteration of cardiolipin-dependent mitochondrial coupling in muscle protects against obesity
| Main Author: | Pilot-Storck, Fanny |
|---|---|
| Format: | Dataset |
| Terbitan: |
Mendeley
, 2019
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| Subjects: | |
| Online Access: |
https:/data.mendeley.com/datasets/xz5fx4s7x2 |
Daftar Isi:
- Prola et al. show that mitochondria from muscle of Hacd1 knockout mice have altered membranes lipid composition and cristae shape yielding a reduced respiratory efficiency with neither proton leak nor oxidative stress, and consequently leading to an overall increase in energy expenditure that eventually protects against a diet-induced obesity.