MHC Ligandomes of Reovirus-Treated Tumors
| Main Author: | Murphy, John Patrick |
|---|---|
| Format: | Dataset |
| Terbitan: |
Mendeley
, 2019
|
| Subjects: | |
| Online Access: |
https:/data.mendeley.com/datasets/t5xb48z959 |
Daftar Isi:
- Using a mass spectrometry (MS)-based MHC-I ligandome discovery platform, we determined differential tumor MHC-I ligand expression following treatment with oncolytic reovirus in a murine ovarian cancer model. We then tested the immunogenicity and antitumor immune effects of CD8 T cells specific to these reovirus-induced ligands.