Data for: Practical bioinformatic DNA-sequencing pipeline for detecting oncogene amplification and EGFRvIII mutational status in clinical glioblastoma samples
| Main Author: | Miller, Michael |
|---|---|
| Other Authors: | Waluszko, Aneta, Tome-Garcia, Jessica, Sidorenko, Tatyana, Ye, Fei, Tsankova, Nadejda |
| Format: | Dataset |
| Terbitan: |
Mendeley
, 2019
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| Subjects: | |
| Online Access: |
https:/data.mendeley.com/datasets/nh5y2dddd2 |
Daftar Isi:
- Dataset 1. Sequencing and z-score normalized data results from reference and CNS samples. (A and B) Reference population coverage with means and standard deviations used to calculate z-scores shown at the top. Amplicon z-scores and followed by gene z-scores (A) and EGFRvIII z-scores (B) used to identify focal gene amplification (z-score > 5, final column in A) and EGFRvIII (z-score > 10, final column in B), respectively (EGFR.d2.7 = EGFRvIII). Dataset 2. Reference values used to calculate amplicon and EGFRvIII z-scores from raw coverage matrix and sample metadata. For complete and actively updated repository that uses this reference data, refer to https://github.com/Michael-L-Miller/CoveRageAnalysis (doi:10.5281/zenodo.1220399).