Plaque quantification by coronary computed tomography angiography using intravascular ultrasound as a reference standard: a comparison between standard and last generation computed tomography scanners

Main Author: Andreini, Daniele
Other Authors: Conte, Edoardo, Mushtaq, Saima, Pontone, Gianluca, Ravagnani, Paolo, Galli, Stefano, Guglielmo, Marco, Baggiano, Andrea, Trabattoni, Daniela, Annoni, Andrea, Mancini, Maria Elisabetta, Formenti, Alberto, Muscogiuri, Giuseppe, Fiorentini, Cesare, Bartorelli, Antonio, Pepi, Mauro
Format: Dataset
Terbitan: Mendeley , 2019
Subjects:
Online Access: https:/data.mendeley.com/datasets/chvs8xhr2j
ctrlnum 0.17632-chvs8xhr2j.1
fullrecord <?xml version="1.0"?> <dc><creator>Andreini, Daniele</creator><title>Plaque quantification by coronary computed tomography angiography using intravascular ultrasound as a reference standard: a comparison between standard and last generation computed tomography scanners</title><publisher>Mendeley</publisher><description>Aims The emerging role of coronary computed tomography angiography (CCTA) as a non-invasive tool for atherosclerosis evaluation is supported by data reporting a good correlation between CCTA and intravascular ultrasound (IVUS) for plaque volume quantification. Aim of the present study was to evaluate whether a last generation CT scanner may improve coronary plaque volume assessment using IVUS as standard-of-reference. Methods and results From a registry of 1915 consecutive, all-comers, patients who underwent a clinically indicated IVUS evaluation we enrolled 59 patients who underwent CCTA with a 64-slice CT (Group 1) and 59 patients who underwent CCTA with whole-heart coverage CT scanner (Group 2). Patients who underwent CCTA with unfavourable heart rhythm were not excluded from the analysis. Image quality (4-point Likert scale) focused on plaque analysis was evaluated. Plaque volume quantification by CCTA was compared to IVUS. No difference in clinical characteristics was found between Group 1 and Group 2. Plaque volume quantification by CCTA was considered not feasible in 11 plaques of Group 1 and in 4 plaques of Group 2 (P = 0.09). Higher correlation for plaque volume quantification by CCTA vs. IVUS was demonstrated in Group 2 when compared with Group 1 (r = 0.9888 vs. 0.9499; P &lt; 0.0001). The Bland&#x2013;Altman analysis showed plaque volume overestimation by CCTA of 11.9 mm3 in Group 1 and 4 mm2 in Group 2 (P &lt; 0.001). Effective radiation dose of CCTA was significantly lower in Group 2 vs. Group 1 (2.7 &#xB1; 0.9 vs. 8.1 &#xB1; 3.6 mSv, respectively; P &lt; 0.001). ................................................................................................................................................................................................... Conclusions CCTA using a new scanner generation showed to be an accurate non-invasive tool to assess and quantify coronaryplaque volume. </description><subject>Cardiovascular Imaging</subject><contributor>Conte, Edoardo</contributor><contributor>Mushtaq, Saima</contributor><contributor>Pontone, Gianluca</contributor><contributor>Ravagnani, Paolo</contributor><contributor>Galli, Stefano</contributor><contributor>Guglielmo, Marco</contributor><contributor>Baggiano, Andrea</contributor><contributor>Trabattoni, Daniela</contributor><contributor>Annoni, Andrea</contributor><contributor>Mancini, Maria Elisabetta</contributor><contributor>Formenti, Alberto</contributor><contributor>Muscogiuri, Giuseppe</contributor><contributor>Fiorentini, Cesare</contributor><contributor>Bartorelli, Antonio</contributor><contributor>Pepi, Mauro</contributor><type>Other:Dataset</type><identifier>10.17632/chvs8xhr2j.1</identifier><rights>Creative Commons Attribution 4.0 International</rights><rights>http://creativecommons.org/licenses/by/4.0</rights><relation>https:/data.mendeley.com/datasets/chvs8xhr2j</relation><date>2019-09-13T10:25:39Z</date><recordID>0.17632-chvs8xhr2j.1</recordID></dc>
format Other:Dataset
Other
author Andreini, Daniele
author2 Conte, Edoardo
Mushtaq, Saima
Pontone, Gianluca
Ravagnani, Paolo
Galli, Stefano
Guglielmo, Marco
Baggiano, Andrea
Trabattoni, Daniela
Annoni, Andrea
Mancini, Maria Elisabetta
Formenti, Alberto
Muscogiuri, Giuseppe
Fiorentini, Cesare
Bartorelli, Antonio
Pepi, Mauro
title Plaque quantification by coronary computed tomography angiography using intravascular ultrasound as a reference standard: a comparison between standard and last generation computed tomography scanners
publisher Mendeley
publishDate 2019
topic Cardiovascular Imaging
url https:/data.mendeley.com/datasets/chvs8xhr2j
contents Aims The emerging role of coronary computed tomography angiography (CCTA) as a non-invasive tool for atherosclerosis evaluation is supported by data reporting a good correlation between CCTA and intravascular ultrasound (IVUS) for plaque volume quantification. Aim of the present study was to evaluate whether a last generation CT scanner may improve coronary plaque volume assessment using IVUS as standard-of-reference. Methods and results From a registry of 1915 consecutive, all-comers, patients who underwent a clinically indicated IVUS evaluation we enrolled 59 patients who underwent CCTA with a 64-slice CT (Group 1) and 59 patients who underwent CCTA with whole-heart coverage CT scanner (Group 2). Patients who underwent CCTA with unfavourable heart rhythm were not excluded from the analysis. Image quality (4-point Likert scale) focused on plaque analysis was evaluated. Plaque volume quantification by CCTA was compared to IVUS. No difference in clinical characteristics was found between Group 1 and Group 2. Plaque volume quantification by CCTA was considered not feasible in 11 plaques of Group 1 and in 4 plaques of Group 2 (P = 0.09). Higher correlation for plaque volume quantification by CCTA vs. IVUS was demonstrated in Group 2 when compared with Group 1 (r = 0.9888 vs. 0.9499; P < 0.0001). The Bland–Altman analysis showed plaque volume overestimation by CCTA of 11.9 mm3 in Group 1 and 4 mm2 in Group 2 (P < 0.001). Effective radiation dose of CCTA was significantly lower in Group 2 vs. Group 1 (2.7 ± 0.9 vs. 8.1 ± 3.6 mSv, respectively; P < 0.001). ................................................................................................................................................................................................... Conclusions CCTA using a new scanner generation showed to be an accurate non-invasive tool to assess and quantify coronaryplaque volume.
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institution Universitas Islam Indragiri
affiliation onesearch.perpusnas.go.id
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first_indexed 2020-04-08T08:21:07Z
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