Perubahan Kadar interleukin-6 (IL-6) di air mata dan serum darah pada graves orbitopati sebelum dan sesudah pemberian kortikosteroid intravena
| Main Authors: | RETNA MUSTIKA DEWI, Prof. Dr. dr. Agus Supartoto, Sp.M(K) dr. Tri Wahyu Widayanti, SpM(K), M.Kes., KVR |
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| Format: | Thesis |
| Terbitan: |
ILMU KESEHATAN MATA Universitas Gadjah Mada
, 2022
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| Subjects: | |
| Online Access: |
http://etd.repository.ugm.ac.id/penelitian/detail/210093 |
Daftar Isi:
- Median of serum IL-6 in patients with moderate-severe active Graves orbitopathy after intravenous injection of methylprednisone with a total dose of 3 grams was lower than before therapy. However, the decrease in serum IL-6 levels was not statistically significant.Median IL-6 tears in patients with moderate-severe active Graves orbitopathy after intravenous injection of methylprednisone with a total dose of 3 grams were higher than before therapy. However, the increase in tear IL-6 levels was not statistically significant.A significant relationship was found between changes in serum IL-6 and improvement in the Schimer test. There was no significant relationship between changes in serum IL-6 and tears on improvement in OSDI, CAS scores, and TBUT after Methylprednisolone 3 gram injection therapy