Synthesis of Zn-Fe nanoparticles using pulse laser ablation as a contrast agent in magnetic resonance imaging
| Main Authors: | Hikmantiyah, Nurul, Hidayanto, Eko, Khumaeni, Ali |
|---|---|
| Format: | Article info application/pdf Journal |
| Bahasa: | eng |
| Terbitan: |
Diponegoro University Semarang Indonesia
, 2019
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| Online Access: |
https://ejournal2.undip.ac.id/index.php/jpa/article/view/6458 https://ejournal2.undip.ac.id/index.php/jpa/article/view/6458/3538 |
Daftar Isi:
- Synthesis of zinc oxide nanoparticles, iron oxide nanoparticles and Zn-Fe nanoparticles using pulse laser ablation method has been conducted. Experimentally, a pulse Nd:YAG laser (1064 nm, 7 ns, 35 mJ) was directed and focused on a metal plates of pure Zn and Fe, which are placed in the liquid medium of polyvinyl pyrrolidone (PVP). The PVP functions as a stabilizer agent. The results show that the produced nanoparticles have a spherical shape with an averaged diameter of Zn-Fe nanoparticles of 13 nm. FTIR and XRD test results of Zn-Fe nanoparticles show characteristics of Zn-Fe compounds. The examination of Zn-Fe nanoparticles as MRI contrast agents was carried out by varying the concentration of nanoparticles. Cenh calculation results showed the highest contrast enhancement occurred at a concentration of 1.25 mM with a value of 64.26% for T1 weighted images, and 81.52% for T2 weighted images. The SNR calculation results show the highest value at a concentration of 1.25 mM of 70.52 for T1 weighted images. The highest SNR value in the T2 weighted image at a concentration of 0.156 mM of 165.09.