Dammarane-Type Triterpenoids from The Stembark of Aglaia argentea (Meliaceae)

Main Authors: Hidayat, Ace Tatang, Farabi, Kindi, Farida, Ida Nur, Haikal, Kansy, Nurlelasari, Nurlelasari, Huspa, Desi Harneti Putri, Maharani, Rani, Supratman, Unang, Shiono, Yoshihito
Format: Article info application/pdf eJournal
Bahasa: eng
Terbitan: Syarif Hidayatullah State Islamic University , 2018
Online Access: http://journal.uinjkt.ac.id/index.php/valensi/article/view/7065
http://journal.uinjkt.ac.id/index.php/valensi/article/view/7065/pdf_2
http://journal.uinjkt.ac.id/index.php/valensi/article/downloadSuppFile/7065/796
Daftar Isi:
  • Two dammarane-type triterpenoids, 20S,24S-epoxy-3α,25-dihydroxydammarane (1) and 3α-acetyl-20S,24S-epoxy-3α,25-dihydroxydammarane (2), have been isolated from the stembark of Aglaia argentea. The chemical structure of compounds (1 and 2) were identified by spectroscopic evidences including UV, IR, 1D-NMR, 2D-NMR and MS as well as by comparing with previously reported spectral data. Those compounds were isolated from this plant for first time. Compounds (1 and 2) showed cytotoxic activity against P-388 murine leukemia cells with IC50 values of 23.96 and 8.14 mM, respectively.DOI:http://dx.doi.org/10.15408/jkv.v4i1.7065