Association of Obesity and Negative Acid-Fast Bacilli Finding Among Pulmonary Tuberculosis Patients with Type 2 Diabetes Mellitus

Main Authors: Magfira, Nadya, Mokoagow, Md Ikhsan, Kshanti, Ida Ayu, Helda, Helda
Other Authors: Fatmawati General Hospital
Format: Article info Cross sectional analytical study application/pdf Journal
Bahasa: eng
Terbitan: Department of Epidemiology, FoPH, UI , 2020
Subjects:
Online Access: http://journal.fkm.ui.ac.id/epid/article/view/3470
http://journal.fkm.ui.ac.id/epid/article/view/3470/pdf_1
Daftar Isi:
  • Obesity is known as protective factors of pulmonary tuberculosis (PTB) innon-diabetes mellitus population. However, it’s effect on PTB in type 2diabetes mellitus (T2DM) patient is unclear. The study aims to determinethe association between obesity and PTB in patient with T2DM. A crosssectional study was held in in-patient, The Department of Internal Medicine, Fatmawati General Hospital from January 2015 to December 2017.This study includes patient with T2DM who had been diagnosed with PTBand age > 18 years old. In this study negative Acid-fast-bacilli (AFB)founding defined as patient’s sputum is negative by smear microscopy,while obesity define as body mass index > 24.9 kg/m2. From 363 PTBpatient with T2DM, 22.59% were obese. Results showed that prevalenceof negative AFB founding in PTB patients with T2DM was 81.82% and itwas solely associated with obesity (p:0.002, OR=6.36, 95%CI 1.9-21). Obesepatients were likely to have negative AFB founding. It suggested thatdiagnosing PTB in patient with T2DM and obese can’t be solely based onbacteriological confirmation