Antibacterial Activity of Ethyl Acetate Extract of Red Ginger (Zingiber officinale Roscoe var. Sunti) Against Bacteria of Staphylococcus aureus and Escherichia coli
| Main Authors: | Purbaya, Sari, Aisyah, Lilis Siti, Jasmansyah, Jasmansyah, Arianti, Wenny Eliza |
|---|---|
| Format: | Article info application/pdf eJournal |
| Bahasa: | ind |
| Terbitan: |
Department of Chemistry, Faculty of Sciences and Informatics, Jenderal Achmad Yani University
, 2018
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| Online Access: |
http://jkk.unjani.ac.id/index.php/jkk/article/view/12 http://jkk.unjani.ac.id/index.php/jkk/article/view/12/6 |
Daftar Isi:
- Rimpang jahe merah (Zingiber officinale Roscoe var. sunti) salah satu herbal yang banyak dimanfaatkan sebagai obat tradisional. Penelitian kali ini adalah untuk mengetahui metabolit sekunder yang terkandung didalam tanaman rimpang jahe merah dan aktivitas antibakteri terhadap bakteri Staphylococcus aureus dan Escherichia coli. Sebanyak 483,2 gram serbuk jahe merah diekstraksi dengan metode maserasi didapatkan ekstrak etil asetat 15,85 g. Uji aktivitas antibakteri ekstrak jahe merah terhadap bakteri S. aureus dan E. coli menggunakan metode mikrodilusi menunjukkan ekstrak etil asetat dapat menghambat pertumbuhan S. aureus dengan MIC (Minimum Inhibitory Concentration) 6,3% dan MBC (Minimum Bactericidal Concentration) 25% dan ekstrak etil asetat rimpang jahe merah dapat MIC (Minimum Inhibitory Concentration) E. coli dengan konsentrasi hambat minimum 25% dan MBC (Minimum Bactericidal Concentration) 50%. Hasil menunjukkan bahwa ekstrak etil asetat rimpang jahe merah paling berpengaruh dan lebih berpotensi dalam menghambat pertumbuhan bakteri Gram positif dibandingkan dengan penghambatan terhadap Gram negatif.
- Red ginger rhizome (Zingiber officinale Roscoe var. Sunti) is one of the herbs that is widely used as traditional medicine. The present study was to determine the secondary metabolites contained in red ginger rhizome plants and antibacterial activity against Staphylococcus aureus and Escherichia coli bacteria. A total of 483.2 grams of red ginger powder was extracted by maceration method obtained from ethyl acetate extract 15.85 g. Antibacterial activity of red ginger extract against S. aureus and E. coli using microdilution method showed that ethyl acetate extract could inhibit S. aureus growth by MIC (Minimum Inhibitory Concentration) 6.3% and MBC (Minimum Bactericidal Concentration) 25% and extract Ethyl acetate red ginger rhizome can Minimum MIC (E. Inhibition Concentration) E. coli with a minimum inhibitory concentration of 25% and MBC (Minimum Bactericidal Concentration) 50%. The results showed that the red ginger rhizome ethyl acetate extract was the most influential and had more potential to inhibit the growth of Gram positive bacteria compared to inhibition of Gram negative.