AKTIVITAS ANTIOKSIDAN SENYAWA KUMARIN TER-O-GERANILASI DARI AKAR Limonia acidissima L.
| Main Authors: | Tjahjandarie, Tjitjik Srie, Saputri, Ratih Dewi, Tanjung, Mulyadi |
|---|---|
| Format: | Article info application/pdf Journal |
| Bahasa: | eng |
| Terbitan: |
Faculty of Pharmacy, Universitas Mulawarman, Samarinda, Indonesia, 75117
, 2017
|
| Online Access: |
https://jtpc.farmasi.unmul.ac.id/index.php/jtpc/article/view/143 https://jtpc.farmasi.unmul.ac.id/index.php/jtpc/article/view/143/136 |
Daftar Isi:
- Five O-geranylated coumarins namely as auraptene (1), 7-((2’E,6’E)-5’-hydroxy-3’,7’-dimethylocta-2’,6’-dienyloxy)coumarin (2), 7-(2’E,5’E)-7’-hydroxy-3’,7’-dimethylocta-2’,5’-dienyloxy) coumarin (3), 6-methoxy-7-oxygeranylcoumarin (4), and 8-oxygeranylpsoralen (5) were isolated from the roots of Limonia accidissima L. Their structures were determined based on spectroscopic data such as UV, IR, MS and NMR. Compounds 1–5 were evaluated for their radical scavenging against 2,2-diphenyl-1-picrylhydrazyl (DPPH), showing their IC50 were 462; 13; 260; 210 and 234 μg/ml, respectively. Keywords: Limonia accidissima L., O-geranylated coumarins, antioxidant activity, DPPH