The Effect of Giving Trigona Honey and Honey Propolis Trigona to the mRNA Foxp3 Expression in Mice Balb/c Strain Induced by Salmonella Typhi
| Main Author: | Rosdiana Natzir, Rosdiana Natzir |
|---|---|
| Format: | Article |
| Bahasa: | eng |
| Terbitan: |
American Journal of Biomedical Research, Science & Education Publishing
, 2017
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| Subjects: | |
| Online Access: |
http://repository.unhas.ac.id/handle/123456789/25640 |
Daftar Isi:
- Abstract Immune balance during infection is important to support both the defense of body immune system and prevent excessive immune response. Protein Foxp3, a transcription factor of regulatory T cell has pivotal roles in balancing body immune system. Honey and Propolis have proved their effects to both the proinflamatory and anti inflammatory responses but their effects to the Foxp3 expression need to be investigated. This study was investigated the effect of giving Trigona honey and honey propolis Trigona to the mRNA Foxp3 expression in Balb/c mice induced Salmonella typhi. Results of the study indicated that honey propolis Trigona had the highest effect to the mRNA Foxp3 expression followed by Trigona honey. Both Trigona honey and honey propolis had immunomodulatory effects through the Foxp3 mRNA expression.