ISOLASI α-MANGOSTIN DARI KULIT BUAH MANGGIS (Garcinia mangostana L.) DAN UJI AKTIVITAS ANTIBAKTERI TERHADAP Bacilus cereus
| Main Author: | Idawati, Sri |
|---|---|
| Format: | Thesis NonPeerReviewed Book |
| Bahasa: | eng |
| Terbitan: |
, 2018
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| Subjects: | |
| Online Access: |
http://eprints.unram.ac.id/10933/1/ARTIKEL%20ALFA%20MANGOSTIN%20JPKIK%20MFH.pdf http://eprints.unram.ac.id/10933/ |
Daftar Isi:
- One of the fruit plants that has the potential as a drug is mangosteen, especially on the skin of the fruit. The main bioactive compound and become a major compound in the mangosteen plant, namely α-mangostin. This research has succeeded in isolating α-mangostin through the extraction process using reflux method using ethanol 96%. Purification done by the recrystallization method with solvent ethanol:aquades (1:1). The result of extraction yield 29,93% and the result of purification obtained the yield of α-mangostin from the weight of the extract was 2,81%. Initial identification of isolates using thin layer Chromatography (TLC) and melting point test. This yellow powder isolate has a melting point of 179,7 oC. Next, structural elucidation is carried out using FT-IR spectroscopy data. Antibacterial activity test isolate compound (α-mangostin) of Bacilus cereus bacteria have the power inhibitory with MIC 0,031 μg/ml.