Analysis of The Essential Oil from Lantana camara Leaves and Its Cytotoxic Potential Against T-47D Breast Cancer Cells
| Main Authors: | Suryati, Suryati, Aziz, Enda Desriansyah, Efdi, Mai, Wahyuni, Fatma Sri, Hefni, Dira |
|---|---|
| Format: | Article info application/pdf eJournal |
| Bahasa: | eng |
| Terbitan: |
Universitas Andalas
, 2021
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| Subjects: | |
| Online Access: |
http://jrk.fmipa.unand.ac.id/index.php/jrk/article/view/364 http://jrk.fmipa.unand.ac.id/index.php/jrk/article/view/364/302 |
Daftar Isi:
- Lantana camara Linn is a family of Verbenaceae which grows wild and is widespread in various both tropical and sub-tropical countries. Isolation essential oil of the L. camara leaves extracted by hydrodistillation and were analyzed by Gas Chromatography-Mass Spectrometry (GC-MS). The results of GC-MS analysis show isocaryophyllene (14.39%), ρ-cymene (8.17 %), β-cubebene (7.8 %), α-pinene (7.64 %), and β-elemene (5.51 %) as the main compound. The cytotoxic activity of the isolated essential oil was highly toxic both to Artemia salina shrimp larvae (LC50 15.92 μg/mL) and to breast cancer cells T-47D (IC50 10.67 μM).