NEUTROPHIL-LYMPHOCYTE COUNT RATIO IN BACTERIAL SEPSIS
| Main Authors: | Luhulima, Danny, ., MARWITO, O, Eva |
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| Format: | Article info application/pdf eJournal |
| Bahasa: | eng |
| Terbitan: |
PERHIMPUNAN DOKTER SPESIALIS PATOLOGI KLINIK INDONESIA
, 2017
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| Subjects: | |
| Online Access: |
http://www.indonesianjournalofclinicalpathology.or.id/index.php/patologi/article/view/792 http://www.indonesianjournalofclinicalpathology.or.id/index.php/patologi/article/view/792/549 |
Daftar Isi:
- Sepsis due to bacterial infection is a matter of very serious medical emergency and requires prompt and proper handling. Variousparameters such as CRP (C-reactive protein) and PCT (procalcitonin) levels are used as a marker of sepsis due to bacterial infection.Sepsis is a condition of systemic inflammation with infection. Physiological response to systemic inflammation determines increasedthe level of neutrophil and reduction of lymphocyte count, therefore combining both of parameters could be a marker in predictingsepsis. The aim of this research was to determine the sensitivity and specificity of the NLCR test in patient with sepsis due to bacterialinfection. This research was conducted by observing 70 SIRS patients aged 14–70 years, at Mitra Keluarga Bekasi Timur Hospitaland Faculty of Medicine Universitas Kristen Indonesia (UKI) Hospital in July-September 2015. This research was an observationalcomparative study with cross-sectional design. Based on ROC curve showed that NLCR test has a sensitivity of 97.8% and specificityof 84.0%, with cut off ≥6.4 (AUC: 0.94, p value <0.05). In conclusion, the NLCR is an ideal and efficient marker to diagnose sepsisdue to bacterial infection with good sensitivity and specificity.