DIAGNOSTIC TEST ON THE FOURTH GENERATION HUMAN IMMUNODEFICIENCY VIRUS IN HIV SUSPECTS
| Main Authors: | ., Sofitri, Nasrul, Ellyza, ., almurdi, ., Efrida |
|---|---|
| Format: | Article info application/pdf eJournal |
| Bahasa: | eng |
| Terbitan: |
PERHIMPUNAN DOKTER SPESIALIS PATOLOGI KLINIK INDONESIA
, 2017
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| Subjects: | |
| Online Access: |
http://www.indonesianjournalofclinicalpathology.or.id/index.php/patologi/article/view/712 http://www.indonesianjournalofclinicalpathology.or.id/index.php/patologi/article/view/712/477 |
Daftar Isi:
- Early diagnosis for Human Immunodeficiency Virus (HIV) infection can reduce the risk of transmission. Acute infection diagnosisbased on antigen assay or ribonucleic acid test (RNA/proviral DNA). Enzyme Immunoassay (EIA) fourth generation can detect HIVp24 antigen and antibodies simultaneously. The research objective was to determine the diagnostic value of the fourth-generationHIV testing in HIV suspects. This was a diagnostic test with cross-sectional design, perfomed on 70 patients with suspected HIVwho came to the Volunters Counselling and Testing clinic (VCT) Dr. M. Djamil Hospital Padang from Maret 2015 to Maret 2016.The study was aimed to measure the diagnostic values (sensitivity, specificity, positive predictive value, negative predictive value) offourth generation HIV tests with Enzyme Linked Fluorescent Assay (ELFA) against Reverse Transcriptase Polymerase Chain Reaction(RT-PCR) RNA HIV and analyzed using crosstab 2×2. The were 70 subjects, consisting of 46 males (65.7%) and 24 females (34.3%)with a diagnosis of HIV suspects. Mean of age was 27.7 year. Heterosexual was the major transmision of HIV. The sensitivity andspecificity of fourth-generation HIV test against HIV RNA were 95% and 96% respectively, and the positive predictive value andnegative predictive value were 97 and 92%, respectively.