TOLAK UKUR FUNGSI HATI BERDASARKAN DERAJAT FIBROSIS PENYAKIT HATI KRONIS
| Main Authors: | Rahmafitria, Rahmafitria, Mutmainnah, Mutmainnah, Samad, Ibrahim Abdul |
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| Format: | Article info application/pdf eJournal |
| Bahasa: | eng |
| Terbitan: |
PERHIMPUNAN DOKTER SPESIALIS PATOLOGI KLINIK INDONESIA
, 2016
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| Subjects: | |
| Online Access: |
http://www.indonesianjournalofclinicalpathology.or.id/index.php/patologi/article/view/498 http://www.indonesianjournalofclinicalpathology.or.id/index.php/patologi/article/view/498/243 |
Daftar Isi:
- Evaluating the degree of liver fibrosis degree is invasive as well as uncomfortable, therefore, non invasive examinations such as liver function tests and elastography (Fibro Scan) as a predictor‘s device of liver fibrosis degree are necessary. The aim of this study was to know the differences of liver function parameters based on the fibrosis degree in patients with chronic liver disease. This study was a cross sectional design using data from chronic liver disease patients treated at the Dr. Wahidin Sudirohusodo Hospital. The elasticity of the liver was measured using a fibro scan device during June 2010–July 2011. The analysis was carried out by ANOVA test on various parameters of liver function particularly on the fibrosis degree in chronic liver disease. In this study PT, albumin, total bilirubin and platelet count showed a significant difference of 0.019, 0.009, 0.017 and 0.000 respectively. The mean values of PT and total bilirubin were significantly higher in the high degree of fibrosis compared to those with medium and low degree of fibrosis in the chronic liver disease patients. Based on this study, the mean albumin levels and platelet count were significantly lower in the high degree of fibrosis compared with the medium and low degree of fibrosis, however, no significant differences in AST, ALT, APTT and GGT were found.