SINDROM HORMON ANTIDIURETIK BERLEBIH

Main Authors: Suryatenggara, Arleen N., Astrawinata, Dalima A. W.
Format: Article info application/pdf eJournal
Bahasa: eng
Terbitan: PERHIMPUNAN DOKTER SPESIALIS PATOLOGI KLINIK INDONESIA , 2016
Subjects:
Online Access: http://www.indonesianjournalofclinicalpathology.or.id/index.php/patologi/article/view/371
http://www.indonesianjournalofclinicalpathology.or.id/index.php/patologi/article/view/371/119
Daftar Isi:
  • Syndrome of Inappropiate Antidiuretic Hormone (SIADH) is a condition caused by excessive antidiuretic hormone (ADH) secretion. High level of ADH increse water reabsorption in the kidney. This syndrome is characterized by hyponatremia, plasma hypo-osmolality, urine osmolality less than 100 mOsm/kg, elevated urine sodium, euvolemia, with normal renal, adrenal, and thyroid function. SIADH could be the result of ectopic ADH caused by malignant cells, drug-induced, baroreceptor lesion, and other problems. Main treatment for SIADH is intended to overcome the underlying diseases. Other approaches are by fluid restriction, salt supplementation, and the use of drugs inducing diabetes insipidus or V2 receptor antagonist.