PLATELET AGGREGATION IN ACUTE CORONARY SYNDROME
| Main Authors: | Sulianty, Sulianty, Aman, Adi K |
|---|---|
| Format: | Article info application/pdf eJournal |
| Bahasa: | eng |
| Terbitan: |
PERHIMPUNAN DOKTER SPESIALIS PATOLOGI KLINIK INDONESIA
, 2016
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| Subjects: | |
| Online Access: |
http://www.indonesianjournalofclinicalpathology.or.id/index.php/patologi/article/view/344 http://www.indonesianjournalofclinicalpathology.or.id/index.php/patologi/article/view/344/93 |
Daftar Isi:
- Haemostatic system is the mechanism that controls response of bleeding or thrombosis, so that thrombogenesis and fibrinolysis are in balance. Obstruction of brain and heart vascular system often occurred, because of the hyperactivity of thromboses function that causes thrombosis. CBC, blood glucose, lipid profile and cardiac enzyme assay were performed on acute coronary syndrome patients at the Emergency Department as well as at the normal control. In this study, each group consist of 10 patients. Platelet aggregation test was measured with turbidimetric method using Helena Agram aggregometer. ADP and epinephrine 5 and 10 μM were used as the agonists. here was significant difference in the mean total cholesterol, LDL and blood sugar level in the acute coronary syndrome patients than the control group. Platelet aggregations with ADP 1 and 5 μM were significantly different in the acute coronary syndrome patients than the control one. In this study were found patients aged above 50 years old have platelet aggregation with ADP 10 μM, which differ significantly than the control group.