Profile Trigliserid Serum on Hypercholesterolemi Rats by Ethanol Extract of Lingzhi Mushroom (Ganoderma lucidum)
| Main Authors: | Ayuningtyas, Eka Dewi, Wahyuni, Arifah Sri |
|---|---|
| Format: | Book eJournal |
| Bahasa: | eng |
| Terbitan: |
Jurnal Medika Planta
, 2013
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| Subjects: | |
| Online Access: |
http://majour.maranatha.edu/index.php/jmp/article/view/974 |
Daftar Isi:
- Introduction: Lingzhi mushroom (Ganoderma lucidum) is the herbal medicine that have antiinflammatory, hepatoprotective, hypoglycemic, hypotensive, and hypolipidemic activities. Lingzhi mushroom contain triterpenoid that reported has hypolypidemic activity by cholesterol syntesis inhibitor.Objectives: Determine the triglyceride profile on hypercholesterolemi rats by ethanol extract of lingzhi mushroom.Methods: There are 20 rats that were divided 4 groups. Group 1 was given standard diet. Group 2,3,4 were given high-fat diet then given standard diet and aquadest 2.5 ml/200mg body weight (for group 2), diet standar and ethanol extract of lingzhi mushroom 200, 400 mg/kg body weight (for group 3, 4).Results: After treatment, levels triglycerides in all groups decrease. The decreasing triglyceride levels did not significantly between groups 3, 4 with group 2 and group 1 (p>0.05).Conclusion: Administration ethanol extract of lingzhi mushroom did not affect on the level triglyceride in hipercholesterolemi rats.