The Effect of Camellia sinensis L. Extract on the Learning Process and Memory on Male Mice Swiss Webster Strain by Maze Learning Test

Main Authors: Evacusiany, Endang; Bagian Farmakologi Fakultas Kedokteran Universitas Kristen Maranatha, -, Djusena, Ambarsary, Riry; Bagian Farmakologi Fakultas Kedokteran Universitas Kristen Maranatha
Format: application/pdf eJournal
Bahasa: eng
Terbitan: Jurnal Medika Planta , 2013
Subjects:
Online Access: http://majour.maranatha.edu/index.php/jmp/article/view/887
Daftar Isi:
  • Introduction: The ability of brain can be decreasing with the aging process. Consuming the black tea can be good for the brain, it assumed because the benefit of the black tea is delay the damage cells of the brain.Objective: the aim of this experiment is to asses the effect of black tea (Camellia sinensis L.) leaf water extract on learning process and memory in mice.Methods: This experiment is use the experimental prospective method using Random Complete Design. Male mice of Swiss Webster strain were divided into four groups (n=6). The treated groups were administered with black tea leaf water extract 6,5mg/kgBw; 32,5 mg/kgBW; and 65 mg/kgBW 10 days. The control group was administered with aquadest in 10 days. Everyday, mice were tested on the maze learning box. Observe the mice's travel time from the start box until goal area on maze learning box. Data was analyzed using one way ANVA method with a=0.05. Results: the result shows that there is a decreasing of travel time mg/kgBW and control group even it's not significantly.Conclusion: Black tea leaf water extract is not effective to increasing the learning process and memory in mice.