COMPARISON OF BEETLE NUT SEED (Areca cathecu L) EXTRACT TABLET THERAPY RESULT IN INFESTATION INTESTINAL WORM AT MUMBULSARI-JEMBER
| Main Authors: | Utami, Wiwien S.; Faculty of Medicine, Jember University, Hermansyah, Bagus; Faculty of Medicine, Jember University, -, Nuri; Faculty of Pharmacy, Jember University, Wicaksono, Yudi; Faculty of Pharmacy, Jember University, Gemawan, Taufiq; Faculty of Pharmacy, Jember University |
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| Format: | application/pdf eJournal |
| Bahasa: | eng |
| Terbitan: |
Jurnal Medika Planta
, 2013
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| Subjects: | |
| Online Access: |
http://majour.maranatha.edu/index.php/jmp/article/view/859 |
Daftar Isi:
- Worm disease is a disease that can be suffered by all ages. According to WHO data, the number of worms to reach one billion people in the world, and about 40-60 percent of Indonesia's population is infected with worms. Indonesia is included in a tropical country so that the various parasites thrive in the cycle so it can easily infect humans. According to the study of Kurniawati (2008) conducted at the elementary school age children in Mumbulsari Jember, infection was found positive by Ascaris lumbricoides with the highest percentage (68.96%), Enterobius vermicularis (34.48%), and hookworm (17.24% ). Empirically beetle nut is a drug effective against intestinal worms.Objective: to compare the therapeutic outcomes of beetle nut extract’s tablets (Areca cathecu L) in patients with intestinal nematode infestation in mumbulsari, Jember with standard treatment. Method: The design of the study is a randomized control clinical trial methods. Subjects who had tested positive for infection by stool examination will be divided into two groups randomly, group A as a treatment group given treatment tablets of extract of beetle nut, while group B as a control group given a standard drug that is pirantel pamoat. Two weeks later examined the amount of EPG (egg per gram) in stool samples and the results were analysed statisticaly using two way Anova. Result: The results of statistical analysis of two way ANOVA p <0.05 indicates the type of material factors of treatment had the same average decrease in the number of eggs. Factor type of intestinal worms had different average decrease in the number of eggs while the interaction factor showed an equal decrease number of eggs. In the Tukey-HSD test showed that Ascaris and Hookworm have a better therapeutic outcome than Trichuris trichiura. Conclusion: extract of beetle nut has an equal therapeutic outcome with pirantel pamoat on infestation of hookworm and Ascaris worms and have a better therapeutic outcome on infestation of Trichuris trichiura worm.