UJI EFEK TONIKUM VARIASI DOSIS EKSTRAK ETANOL BUAH PARE (Momordica charantia L.) PADA MENCIT JANTAN (Mus musculus L.)
| Main Authors: | Parmadi, Anom, Ubaidilla, Farid |
|---|---|
| Format: | Article info application/pdf eJournal |
| Bahasa: | ind |
| Terbitan: |
Jurnal Kesehatan SAMODRA ILMU
, 2016
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| Online Access: |
http://ejournal.stikes-yogyakarta.ac.id/index.php/jksi/article/view/78 http://ejournal.stikes-yogyakarta.ac.id/index.php/jksi/article/view/78/88 http://ejournal.stikes-yogyakarta.ac.id/index.php/jksi/article/downloadSuppFile/78/3 |
Daftar Isi:
- Background: Fruit Pare (Momordica charantia L.) is a medicinal plant since the days of ourancestors has been used to cure various diseases. one of them to give a fresh effect is mainlyto provide a stimulant effect. Pare fruit contains saponins, flavonoids, polivenol, triterpenoids,alkaloids, momordisin, glycosides and kukurbitasin.Method: Pare as a tonic fruit research is experimental research. Intake of fruit ethanolextract Pare using maceration method. Number of male mice used were 25 tail and dividedinto five groups. The first group was treated orally with a dose of caffeine 13 mg / kg. Eachgroup II, III and IV were treated with the ethanol extract oral dose of 50 mg / kg, 100 mg / kgand 200 mg / kg. V group was treated orally with coconut oil volume of 0.5 ml / 20 grams bodyweight. Data obtained from the tonic effects Mice time to defend themselves when swimming.The data obtained were statistically analyzed using ANOVA test using SPSS 18.0 for windows.Result: Pare fruit ethanol extract has a tonic effect on test animals, demonstrated a meanvalue of the extract I (50 mg / kg) with 6.40 minutes, extract II (a dose of 100 mg / kg) with13.20 minutes and extracts III ( dose of 200 mg / kg) with 21.40 minutes.Conclutions:Pare fruit ethanol extract has a tonic effect on test animals and the tonic effectof the ethanol extract of the fruit Pare same compared with the ethanol extract of caffeine atdoses of 200 mg / kg dose of caffeine and13mg/kg.Keywords: Tonic effect, Momordica charantia L, Male mice1