Senyawa Turunan Oleanan dari Kulit Batang Melochia umbellata (Houtt) Stapf var. Degrabrata K dan Bioaktivitasnya
| Main Authors: | Usman, Usman, Soekamto, Nunuk H., Usman, Hanapi, Ahmad, Ahyar |
|---|---|
| Format: | Article info application/pdf Journal |
| Bahasa: | eng |
| Terbitan: |
Chemistry Department, Pattimura University
, 2014
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| Online Access: |
https://ojs3.unpatti.ac.id/index.php/ijcr/article/view/1938 https://ojs3.unpatti.ac.id/index.php/ijcr/article/view/1938/1509 |
Daftar Isi:
- Oleanan derivated 3-acetyl-12-oleanen-28-oat has been isolated from the n-hexane fraction of M. umbellata (Houtt) Stapf var. degrabrata K. bark. The molecular structure were determined by IR spectroscopy, 1D and 2D NMR (1H, 13C, DEPT, COSY, HMQC and HMBC) data analysis. Bioactivity tested results indicated that the compound was toxic to A. salina with LC50 value was 361.93 mg/mL. At the concentration of 1000 mg /mL 3acetyl-12-oleanen-28-oat gave the highest inhibition to bacteria B. subtilis and the fungus C. albicans with the inhibited zone diameter was 15.8 mm and 15.2 mm, res.