Efek Daun Dewa (Gynura pseudo-china Aug D.C.) terhadap Peningkatan Trombosit Tikus Putih yang Diinduksi Hidroksi Urea
Main Authors: | Winarno, M. Wien; Puslitbang Biomedis dan Farmasi, Badan Litbangkes, Suciati, Yesi; JF MIPA UHAMKA, Jakarta, Sediarso, H.; JF MIPA UHAMKA, Jakarta |
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Other Authors: | BADAN LITBANGKES KEMENKES |
Format: | Article application/pdf eJournal |
Bahasa: | ind |
Terbitan: |
Center for Biomedical and Basic Technology of Health,National Institute of Health Research
, 2012
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Online Access: |
http://ejournal.litbang.depkes.go.id/index.php/jki/article/view/1297 |
Daftar Isi:
- Daun dewa (Gynura pseudo-china Aug. DC), empirically used as anti-inflammation, antiĀ diare, anti-tumor, and anti-fungus Additionally, it also used to prevent blood vessel contriction, and stimulate the immune system. The leaf from Daun Dewa empirically used to dengue fever treatment. In this study, 25 white rats Wistar strain were used which is divided into 5 groups : 1) control group, 2) study group, which is divedid into 3 doses (100 mg, 200 mg, 400 mg/200g body weight) and 3) the normal control group (without induced). Hydroxy urea dose 27 mg/200 g body weight 2 times a day for induced The treatment given 8 days dividing and every 2 days once done taking 0,5 ml of blood via the tail vein. Result showed ethanol leaf extract of Daun dewa dose 100 mg,200 mg, and 400 mg/ 200 g body weight increase thrombocyte. Incease thrombocyte going on forth day after the test dose, and the sixth day amount thrombocyte have reached normal. Keywords: Daun dewa (Gynura pseudo-china Aug. DC), ethanol extract, thrombocyte