Pengaruh Pemberian Ekstrak Air Daun Jati Belanda (Guazuma Ulmifolia Lamk.) terhadap Kadar Lipid Darah pada Tikus Jantan
| Main Authors: | Sukandar, Elin Yulinah; Sekolah Farmasi, Institut Teknologi Bandung, ., Elfahmi; Sekolah Farmasi, Institut Teknologi Bandung, ., Nurdewi; Sekolah Farmasi, Institut Teknologi Bandung |
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| Format: | application/octetstream eJournal |
| Bahasa: | eng |
| Terbitan: |
Universitas Kristen Maranatha
, 2010
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| Online Access: |
http://majour.maranatha.edu/index.php/jurnal-kedokteran/article/view/129 |
Daftar Isi:
- Jati belanda (Guazumaulmifolia Lamk) has traditionally been used as a slimming agent. This study attempted to determine the effect of water extract of jati belanda on the blood lipid concentration of Wistar rats induced - hyperlipidemia. These rats were divided into four groups, each consisting of five rats. Three of these groups were subsequently induced by (1) jati belanda extract at a dose of 25 mg/kg body weight, (2) jati belanda extract at a dose of 50 mg/kg body weight, and (3) simvastatin. The fourth was the control group. The extract as well as the simvastatin was given orally for 14 days whereas the control group received vehicle. Blood lipid concentration was determined on day 7 and day 14. The result of this study was analyzed statistically using SPSS program. The result showed that the group induced with water extract of jati belanda at a dose of 50 mg/kg body weight had a significantly lower level of total cholesterol and LDL cholesterol than the control group.