Hubungan Kadar Kolesterol LDL dengan Tingkat Keparahan Pasien Stroke Perdarahan Intraserebral Onset 24 jam yang Dihitung dengan NIHSS di Stroke Unit RSSA
| Main Author: | Waly, Armyd Haleluya |
|---|---|
| Format: | Thesis NonPeerReviewed Book |
| Bahasa: | eng |
| Terbitan: |
, 2017
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| Subjects: | |
| Online Access: |
http://repository.ub.ac.id/167975/1/Armyd%20Haleluya%20Waly.pdf http://repository.ub.ac.id/167975/ |
Daftar Isi:
- Low blood LDL cholesterol level is one of risk factors of intracerebral hemorrhagic stroke. Cholesterol possesses important structural role within plasma membrane and act as the main lipid core within plasma membrane, therefore sufficient cholesterol level is required to support the quality and effectivity of the blood vessel to protect from rupturing. Low LDL cholesterol level plays a detrimental role in smooth muscle lining necrosis in medial artery vessels. Disrupted endothelium will be more vulnerable towards microaneurysm development. Furthermore, some studies delineate the fatal risk in PIS on patients with LDL cholesterol level <77,48 mg/dl, which has 3 times higher risk of rupturing compared with patients with LDL > 77,48 mg/dl. The increased LDL cholesterol concentration of 18,76 mg/dl is linked with 15% decrease in hemorrhagic intracerebral stroke, the decrease of LDL-C concetration is also associated with increased risk of intracerebral hemorrhage stroke. Our study is conducted using medical record of Intracerebral hemorrhagic stroke pateints in Saiful Anwar General Hospital ( RSSA ) Malang. 35 medical records with LDL-C <77,48mg/dl are found to have various NIHSS score. This study delineate the association between the severity of intracerebral hemorrhage stroke with the low level of LDL-C using National Institutes of Health Stroke Scale (NIHSS), statistical analysis using SPSS shown significance level of < 0,05 which concludes there is a significant difference between the two variables.