POLA PENGOBATAN FLUOR ALBUS DI RUMAH SAKIT UMUM PUSAT NASIONAL DR CIPTO MANGUNKUSUMO SERTA FAKTOR-FAKTOR YANG MEMPENGARUHINYA (ANALISIS DATA REKAM MEDIK TAHUN 2006-2007)
| Main Authors: | Rusdi, Numlil Khaira; Jurusan Farmasi FMIPA-UHAMKA, Trisna, Yulia; RSUPN Cipto Mangunkusumo, Soemiati, Atiek; Departemen Farmasi FMIPA-UI |
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| Format: | Article info application/pdf Journal |
| Bahasa: | eng |
| Terbitan: |
Directorate of Research and Community Engagement, Universitas Indonesia
, 2012
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| Online Access: |
http://psr.ui.ac.id/index.php/journal/article/view/3423 http://psr.ui.ac.id/index.php/journal/article/view/3423/501 |
Daftar Isi:
- The objectives of this study were to know (1) Patients’ characteristics (2) The most etiology of leucorrhoea (3) Association between clinical manifestations or genital symp-toms with etiology of leucorrhoea (4) Therapy management of leucorrhoea by obstet-ric-gynecologist and venereologist (5) Factors influenced the treatment of leucorrhoea (6) Compliance with hospital therapeutic guidelines. The study was cross sectional and retrospective. A total of 437 patients hospitalized from January 2006-December2007 were included. The results showed that leucorrhoea was found in 17,6% of patients at sexually transmitted disease clinic and 82,4% of patients at obstetric-gynecology clinic. The majority of patients were in productive age, married, andhousewife, with most of genital symptoms were pruritus and curd-like vaginal dis-charge. The most of etiology leucorrhoea in this study was candidiasis. Statistically, there were association between genital symptoms with candidiasis and bacterialvaginosis (p<0,05). The specific genital symptoms of candidiasis were pruritus and curd-like vaginal discharge, whereas for bacterial vaginosis were homogeneous andincreased vaginal discharge. There were different treatments of vaginal discharge be-tween obstetric-gynecologist and venereologist. For candidiasis, the obstetric-gyne-cologist preferred to use fluconazole, and metronidazole+nystatin (Flagistatin®); whereas the venereologist used clotrimazole and itraconazole. For bacterial vaginosis, obstet-ric-gynecologist used clindamycin and metronidazole+nystatin (Flagistatin®), while venereologist preferred to use metronidazole. For trichomoniasis there was no different treatment between obstetric-gynecologist and venereologist. In pregnancy, antibiot-ics used to treat leucorrhoea were clindamycin, fluconazole, metronidazole+nystatin (Flagistatin®), metronidazole, and nystatin. Prescribing compliance with the hospi-tal therapeutics guidelines were 37,8%. The type of antibiotics used were azitromycin, clindamycin, clotrimazole, doxycycline, fluconazole, itraconazole, ketoconazole, andmetronidazole. Statistics analysis by Logistic regression (Cl 95%) showed that factors influenced the treatment of leucorrhoea included genital symptoms (OR = 0,975),risk factors (OR = 0,917), etiology (OR = 1,103), and comorbid diseases (OR = 1,387).Key words : leucorrhoea, vaginal discharge, profile of antibiotics for leucorrhoea, obstetric-gynecologist, venereologist.