PHENOLIC COMPOUND FROM THE STEM BARK OF MANGGIS HUTAN (Garcinia bancana Miq.) AND THEIR ANTIOXIDANT ACTIVITY

Main Authors: Muharni, Muharni, Supriyatna, Supriyatna, Bahti, Husein H. , Dachriyanus, Dachriyanus
Format: Article PeerReviewed application/pdf
Terbitan: Jurusan Kimia FMIPA UGM , 2009
Subjects:
Online Access: http://eprints.unsri.ac.id/5881/1/IJC_2009_(2).pdf
http://eprints.unsri.ac.id/5881/
Daftar Isi:
  • A phenolic compoud, (-)-epicatechin, was isolated from the stem bark of Garcinia bancana. The structure of this compound was determined base on spectroscopic data such as including UV, IR, 1-D, 2-D NMR, and comparison with the reported data. Biological activity of this compound at free radical scavenging activity by 1,1-diphenyl-2-picrylhydrazyl radical (DPPH) and inhibitory xanthine oxidase(XO) activity showed that (-)- epicathechin active at two methods with IC50 value 8.1 and 8.6 μg/mL respectively.