EFFECT OF TAQ1 VITAMIN D RECEPTOR GENE POLYMORPHISM ON THE INCIDENCE OF PULMONARY TUBERCULOSIS
Main Authors: | Sudarto , -, Z. Ahmad, -, K. Arrahmanda, -, D Ergan, -, A. Rasyid, -, Yuwono, - |
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Format: | Proceeding PeerReviewed application/pdf |
Terbitan: |
, 2011
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Subjects: | |
Online Access: |
http://eprints.unsri.ac.id/1783/1/Shanghai_2.pdf http://eprints.unsri.ac.id/1783/ |
Daftar Isi:
- Tuberculosis (TB) still world’s and Indonesia problem. Approximately one third of the world population ever infected with Mycobacterium tuberculosis (Mtb), but only about 10% become pulmonary TB. Presumably there is influence of individual genetic factors to TB infection. Resistance to TB influenced by genetic factors that control immunity. One of gene suspected has a role in immunity against TB is vitamin D receptor gene (VDR gene). Decreasing of this gene function influence to decrease of cellular immunity to Mtb