EFFECT OF TAQ1 VITAMIN D RECEPTOR GENE POLYMORPHISM ON THE INCIDENCE OF PULMONARY TUBERCULOSIS

Main Authors: Sudarto , -, Z. Ahmad, -, K. Arrahmanda, -, D Ergan, -, A. Rasyid, -, Yuwono, -
Format: Proceeding PeerReviewed application/pdf
Terbitan: , 2011
Subjects:
Online Access: http://eprints.unsri.ac.id/1783/1/Shanghai_2.pdf
http://eprints.unsri.ac.id/1783/
Daftar Isi:
  • Tuberculosis (TB) still world’s and Indonesia problem. Approximately one third of the world population ever infected with Mycobacterium tuberculosis (Mtb), but only about 10% become pulmonary TB. Presumably there is influence of individual genetic factors to TB infection. Resistance to TB influenced by genetic factors that control immunity. One of gene suspected has a role in immunity against TB is vitamin D receptor gene (VDR gene). Decreasing of this gene function influence to decrease of cellular immunity to Mtb