High Level of Tumor Necrosis Factor (TNF)-α is a Risk Factor for Preeclampsia
| Main Author: | Anom, I.G.N. |
|---|---|
| Format: | Article info application/pdf Journal |
| Bahasa: | eng |
| Terbitan: |
Indonesian Society of Obstetrics and Gynecology
, 2016
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| Online Access: |
http://inajog.com/ojs/index.php/journal/article/view/306 http://inajog.com/ojs/index.php/journal/article/view/306/295 |
Daftar Isi:
- Objective: To define that elevated TNF-α serum level was the risk factor of preeclampsia in pregnancy. Method: This research is a case-control study. From 56 pregnant women, there are 28 women with preeclampsia and the other 28 women with normal pregnancy. Then the serum level of TNF-α was obtained at Prodia’s clinical Laboratory Denpasar. Data’s normality test was done with Kolmogorov-Smirnov, then an analysis of data was done with Independent Sample Test, predictive value a = 0.05. To define the role of TNF-α level in preeclampsia, Chi-Square test was chosen. Result: From this research we found the average level of TNF-α in preeclampsia (6.64 ± 7.64 pg/ml) was higher than in normal pregnancy (2.42 ± 1.77 pg/ml). Analysis with t-independent test shows that the t-value was 2.85 and p-value was 0.006, which means that the average level of TNF-α between the two group was significantly different (with predictive value, p