PENGARUH KITOSAN TERHADAP SITOLOGI GINJAL TIKUS PUTIH (Rattus sp.) JANTAN YANG DIPAPARI PLUMBUM ASETAT
| Main Author: | Simatupang, Ulina Catarina Jenni; Universitas Dian Nusantara |
|---|---|
| Format: | Article info application/pdf Journal |
| Bahasa: | eng |
| Terbitan: |
Program Studi Biologi, Fakultas Biologi Universitas Medan Area
, 2017
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| Subjects: | |
| Online Access: |
http://ojs.uma.ac.id/index.php/biolink/article/view/848 http://ojs.uma.ac.id/index.php/biolink/article/view/848/824 |
| ctrlnum |
article-848 |
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<dc schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"><title lang="en-US">PENGARUH KITOSAN TERHADAP SITOLOGI GINJAL TIKUS PUTIH (Rattus sp.) JANTAN YANG DIPAPARI PLUMBUM ASETAT</title><creator>Simatupang, Ulina Catarina Jenni; Universitas Dian Nusantara</creator><subject lang="en-US">Pb, Chitosan, Kidny</subject><description lang="en-US">The  study aimed to determine the effect of chitosan on  the kidney of rats (Rattus sp.) exposed to lead acetate. Thirty five male animals weighing 250g were divided into 7 groups:  K group as a control (without treatment), P1  received  Pb (40 mg/kg bw as lead acetate),  while P2, P3, and P4, all received Pb (40 mg/kg bw) and chitosan (0,5%, 0,75%, and 1% respectively). P5 group received only chitosan (1%) and P6 group received acetic acid. After 7 weeks of  treatment, the animals were sacrificed and the kidneys were isolated. Kidney damage was observed with microscopis. Result showed, treatment of Pb (40 mg/kg bw) in male rats caused demage microscopis. Chitosan able to decrease kidney damage resulted from Pb treatment. In conclusion, chotosan has the ability to reduce residue of Pb as well as microstructure damage of rat kidney exposed to Pb.</description><publisher lang="en-US">Program Studi Biologi, Fakultas Biologi Universitas Medan Area</publisher><contributor lang="en-US"/><date>2017-08-31</date><type>Journal:Article</type><type>Other:info:eu-repo/semantics/publishedVersion</type><type>Journal:Article</type><type>File:application/pdf</type><identifier>http://ojs.uma.ac.id/index.php/biolink/article/view/848</identifier><identifier>10.31289/biolink.v3i2.848</identifier><source lang="en-US">BIOLINK (Jurnal Biologi Lingkungan, Industri, Kesehatan); Vol 3, No 2 (2017): Februari; 179-185</source><source>2597-5269</source><source>2356-458X</source><source>10.31289/biolink.v3i2</source><language>eng</language><relation>http://ojs.uma.ac.id/index.php/biolink/article/view/848/824</relation><rights lang="en-US">Copyright (c) 2017 BIOLINK (Jurnal Biologi Lingkungan, Industri, Kesehatan)</rights><recordID>article-848</recordID></dc>
|
| language |
eng |
| format |
Journal:Article Journal Other:info:eu-repo/semantics/publishedVersion Other File:application/pdf File Journal:Journal |
| author |
Simatupang, Ulina Catarina Jenni; Universitas Dian Nusantara |
| title |
PENGARUH KITOSAN TERHADAP SITOLOGI GINJAL TIKUS PUTIH (Rattus sp.) JANTAN YANG DIPAPARI PLUMBUM ASETAT |
| publisher |
Program Studi Biologi, Fakultas Biologi Universitas Medan Area |
| publishDate |
2017 |
| topic |
Pb Chitosan Kidny |
| url |
http://ojs.uma.ac.id/index.php/biolink/article/view/848 http://ojs.uma.ac.id/index.php/biolink/article/view/848/824 |
| contents |
The study aimed to determine the effect of chitosan on the kidney of rats (Rattus sp.) exposed to lead acetate. Thirty five male animals weighing 250g were divided into 7 groups: K group as a control (without treatment), P1 received Pb (40 mg/kg bw as lead acetate), while P2, P3, and P4, all received Pb (40 mg/kg bw) and chitosan (0,5%, 0,75%, and 1% respectively). P5 group received only chitosan (1%) and P6 group received acetic acid. After 7 weeks of treatment, the animals were sacrificed and the kidneys were isolated. Kidney damage was observed with microscopis. Result showed, treatment of Pb (40 mg/kg bw) in male rats caused demage microscopis. Chitosan able to decrease kidney damage resulted from Pb treatment. In conclusion, chotosan has the ability to reduce residue of Pb as well as microstructure damage of rat kidney exposed to Pb. |
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