Comparative efficacy of combination fansidar-sulphate-quinine and fansidar-cbloroquine in mixed malaria infections of P. falciparum - P. vivax in children
| Main Authors: | Liando, A., Rampengan, T. H. |
|---|---|
| Format: | Article info application/pdf eArticle |
| Bahasa: | eng |
| Terbitan: |
Indonesian Pediatric Society
, 2020
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| Online Access: |
https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/2432 https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/2432/2016 |
Daftar Isi:
- From January 1987 until March 1990, 61 children suffering from mixed malaria infections of P. falciparum and P. vivax entered the Department of Child Health Medical School Sam Ratulangi University/Gunung Wenang General Hospital, Manado. Only 41 patients were evaluated as 20 patients did not fulfill the inclusion criteria. Twenty patients were treated with fansidar-quinine (Group I), and 21 patients with fansidar chloroquine (Group II). In group II, the asexual form of P. vivax disappeared in 2 days after having been treated with fansidar-chloroquine. Conversely, in group I the asexual form of P. vivax disappeared after 5 days o[ treatment. Statistical analysis showed a significant difference (p<0.001). No significant difference .could be detected between the duration of asexual parasitemia of P. falciparum in these two groups (p=0.3085). No statistically significant difference could be detected concerning the duration of fever and the length of hospitalization between these rwo groups.