Cerebrospinal Fluid C-reactive Protein in the Diagnosis of Meningitis in Children
| Main Authors: | Soetiono, Soetiman, Sunartini, Sunartini, Machfudz, Soeroyo, S., Setyawati P. |
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| Format: | Article info application/pdf eArticle |
| Bahasa: | eng |
| Terbitan: |
Indonesian Pediatric Society
, 1989
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| Subjects: | |
| Online Access: |
https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/1442 https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/1442/1183 |
Daftar Isi:
- The mortality rate of bacterial meningitis in infants and children is still high (40-50%). Such a mortality rate can be reduced by establishing a prompt and accurate diagnosis. Until now the diagnosis of meningitis is still an important clinical problem.The examination of cerebrospinal fluid C-reactive protein had been done in 44 clinical meningitis patients in the Paediatrics Department, Dr. Sardjito General Hospital qualitatively by means of latex agglutination slide test. Cerebrospinal fluid C-reactive protein was positive in 90% (18120) of bacterial meningitis patients compared to 8.3 % (2124) of non bacterial meningitis patients. The sensivity and specificity of cerebrospinal fluid C-reactive protein were 90% and 91.7% respectively and these value were more sensitive and specific than those of white cell count, absolute polymorphonuclear, glucose and protein levels and the cerebrospinal fluid smear (50-80% and 80-91%, respectively) which had been performed in the diagnosis of meningitis.It can be concluded that the examination of cerebrospinal fluid C-reactive protein can be used as a diagnostic tool of bacterial meningitis.