Cytotoxic Activity of Ethyl Acetate Fraction Of Ethanolic Extract Green Algae (Ulva LACTUCA Linn.) On Mcf-7 Cells
Main Authors: | Asriani Safitri, Eka, Nada Septiawan, Azizah, Pratiwi, Dinda, Emelda, Emelda |
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Format: | Proceeding PeerReviewed Book Thesis |
Bahasa: | eng |
Terbitan: |
, 2019
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Subjects: | |
Online Access: |
http://elibrary.almaata.ac.id/1921/1/APHNI%202019%20Untitled25.pdf http://elibrary.almaata.ac.id/1921/ http://almaata.ac.id |
Daftar Isi:
- Background: Based on data from the GLOBOCAN International Agency for Research on Cancer (IARC), in 2012 there were ± 14 million new cases of cancer and ± 8 million deaths from cancer worldwide. Various treatments were taken to overcome this type of cancer. On of the treatment for breast cancer is herbal medicine. The herbal medicine that are currently being discussed are plants that come from the sea (marine biota), one of which is green algae (Ulva lactuca Linn.). It is not yet known whether the ethanolic extract form and extract fraction also has antioxidant and cytotoxic abilities. Objectives: Conducted a cytotoxic test of the ethyl acetate fraction of green algae extract (Ulva lactuca Linn.) Methods: The method used is MTT Assay Results: IC50 value of Ethyl acetate fraction of ethanolic Extracts of Green Algae is1489,3 μg/ml and Ascorbic acid is 13,99 μg/ml Conclusions: The Ethyl Acetate Fraction of Green Algae Extract (Ulva lactuca Linn.) Have an IC50 value greater than the standard (Doxorubicin). Keywords: Green Algae, Cytotoxic Test, MTT Assay