Immunoinformatics Study on Early 4 Protein of Human Papillomavirus Type 16 for Cervical Cancer Vaccine Peptide Candidate
| Main Authors: | Suryani, Yani, Taupiqurrohman, Opik, Yusuf, Muhammad, Subroto, Toto, Nuswantara, Sukma |
|---|---|
| Format: | Article info application/pdf Journal |
| Bahasa: | eng |
| Terbitan: |
UIN Sunan Gunung Djati Bandung
, 2019
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| Subjects: | |
| Online Access: |
http://journal.uinsgd.ac.id/index.php/biodjati/article/view/5414 http://journal.uinsgd.ac.id/index.php/biodjati/article/view/5414/3511 |
Daftar Isi:
- The aims of this study were to carry out testing of the early 4 protein of type 16 HPV through immunoinformatics meth-ods in an effort to get the peptide vaccine candidate for cervical cancer. The software used are IEDB-AR, CABSdock and Accelrys Discovery Study 4.5. Based on the analysis that sequence of ami-no acid lysine, leucine, leucine, glycine, serine, threonine, tryp-tophan, proline and threonine (KLLGSTWPT) and the sequence of amino acid tyrosine, tyrosine, valine, leucine, histidine, leucine, cysteine, leucine, alanine, alanine, threonine, lysine, tyrosine, pro-line and leucine (YYVLHLCLAATKYPL) are peptide vaccine can-didate for cervical cancer from the early 4 protein of HPV type 16