Seroprevalence and risk factors of herpes simplex virus-2 among pregnant women attending antenatal care at health facilities in Wolaita zone, Ethiopia
| Main Authors: | Anjulo Antehun Alemayehu, Abebe Tamrat, Hailemichael Feleke, Mihret Adane |
|---|---|
| Format: | Journal Book |
| Bahasa: | ind |
| Terbitan: |
Anjulo et al
, 2016
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| Subjects: | |
| Online Access: |
http://opac.unila.ac.id/ucs/index.php?p=show_detail&id=42879 |
Daftar Isi:
- AbstractBackground: Herpes simplex virus type-2 is the common cause of genital ulcer disease worldwide. Genital herpesinfection is a major concern in pregnancy due to the risk of neonatal transmission.Method: A Cross-sectional survey was conducted from December 2013 to September 2014 in randomly selected28 health centers to assess the seroprevalence and risk factors of herpes simplex virus type-2 infection amongpregnant women attending antenatal care in Wolaita zone, Southern Ethiopia. After taking written consent sociodemographic, behavioral, obstetric history and family planning data along with blood samples were collected from252 pregnant women using pre-structured questionnaire. Sera were tested using HerpeSelect-2 ELISA IgG. Dataentry and analysis was done using Epi info 3.5.4 and SPSS 21.00 respectively. Binary logistic regression wasperformed to identify the risk factors associated with HSV-2 seropositivity. P-values less than 0.05 were consideredstatistically significant.Results: The overall seroprevalence of HSV-2 infection was 32.1 % (81/252) among pregnant women in Wolaita zone.Independent predictors of HSV-2 infection includes daily laborer (AOR 1.293, 95 % CI: 1.033â1.739; p = 0.022), havingone sexual partners (AOR 0.476, 95 % CI: 0 .250 â0.904; p = 0.023), history of STDs (AOR 2.822, 95 % CI: 1.50â5.289;p = 0.001) and use of contraceptive (AOR 2.602, 95 % CI: 1.407â4.812; p = 0.002).Conclusion: Overall seroprevalence of HSV-2 infection among pregnant women of Wolaita Zone is high. Awarenesscreation among high risk groups like women who have history of STD should be strengthened. Strengthening thequality of health service delivery and expansion of health service coverage is mandatory.Keywords: Herpes simplex virus type-2, Pregnant women, Genital herpes