PENGARUH PEMBERIAN MINUMAN RINGAN BERKARBONASI TERHADAP PENINGKATAN KADAR GLUKOSA DARAH DAN PERUBAHAN DIAMETER PULAU LANGERHANS PANKREAS TIKUS PUTIH (Rattus norvegicus) JANTAN GALUR Sprague dawley
| Main Author: | FIRINDA SONIYA, 1618011143 |
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| Format: | Bachelors NonPeerReviewed Book Report |
| Terbitan: |
UNIVERSITAS LAMPUNG
, 2020
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| Subjects: | |
| Online Access: |
http://digilib.unila.ac.id/61166/1/ABSTRAK%20%28INGGRIS%20%26%20INDONESIA%29.pdf http://digilib.unila.ac.id/61166/2/SKRIPSI%20FULL.pdf http://digilib.unila.ac.id/61166/3/SKRIPSI%20TANPA%20BAB%20PEMBAHASAN.pdf http://digilib.unila.ac.id/61166/ |
Daftar Isi:
- ABSTRACT THE EFFECT OF CARBONATED SOFT DRINKS CONSUMPTION ON INCREASING THE BLOOD GLUCOSE LEVELS AND ISLETS OF LANGERHANS DIAMETER CHANGES IN MALE Sprague dawley WHITE RATS ( Rattus norvegicus ) by FIRINDA SONIYA Background: The carbonated soft drinks consumption in this world have been increasing rapidly and linking with health problems that involves various organs include the chronic effect to pancreas. This research aims to determine the effect of carbonated soft drinks consumption to increase blood glucose levels and islets of Langerhans diameter changes rats. Method: This research is a post test only control group design experimental study using 28 male white rats Sprague dawley which divided into 4 groups. K group only given an aquadest, P1 group is given carbonated soft drinks 3 ml/day, P2 group 6 ml/day and P3 group 12 ml/day for 30 days. Results: The data of blood glucose levels was analysed by using One Way ANOVA test with result in p value=0.00( <0.05) and then followed by Post Hoc LSD test with result in p value<0.05 for all of groups. The data of diameter Langerhans islets was analysed by using One Way ANOVA test with result in p value=0.394( >0.05) . Conclusion: There is an effect of carbonated soft drinks consumption to increase blood glucose levels and there is no effect of carbonated soft drinks consumption to Langerhans islets diameter changes all 30 days long. Keywords: carbonated soft drink, blood glucose level, diameter changes of Langerhans islet ABSTRAK PENGARUH PEMBERIAN MINUMAN RINGAN BERKARBONASI TERHADAP PENINGKATAN KADAR GLUKOSA DARAH DAN PERUBAHAN DIAMETER PULAU LANGERHANS PANKREAS TIKUS PUTIH ( Rattus norvegicus ) JANTAN GALUR Sprague dawley Oleh FIRINDA SONIYA Latar Belakang: Konsumsi minuman ringan berkarbonasi di dunia telah mengalami peningkatan cukup pesat dan telah dikaitkan dengan timbulnya masalah kesehatan yang melibatkan berbagai organ termasuk efek kroniknya terhadap pankreas. Penelitian ini bertujuan untuk mengetahui pengaruh minuman ringan berkarbonasi terhadap peningkatan kadar glukosa darah dan perubahan diameter pulau Langerhans pankreas tikus. Metode: Penelitian ini merupakan penelitian eksperimental dengan desain post test only control group design menggunakan sampel tikus putih jantan galur Sprague dawley sebanyak 28 ekor dibagi menjadi 4 kelompok. Kelompok K hanya diberi aquades, P1 diberi minumaan ringan berkarbonasi dosis 3 ml/200 g/hari, P2 6 ml/200 g/hari, P3 12 ml/200 g/hari selama 30 hari. Hasil: Data kadar glukosa darah diuji menggunakan One Way ANOVA dan didapatkan penelitian bermakna p=0.00, dilanjutkan dengan post hoc LSD didapatkan perbedaan bermakna pada semua kelompok ( p<0.05) . Sedangkan data diameter pulau Langerhans diuji menggunakan One Way ANOVA didapatkan penelitian tidak bermakna p=0.394 ( p>0.05) . Simpulan: Terdapat pengaruh pemberian minuman ringan berkarbonasi terhadap peningkatan kadar glukosa darah dan tidak terdapat pengaruh pemberian minuman ringan berkarbonasi terhadap perubahan diameter pulau Langerhans pankreas tikus putih ( Rattus norvegicus ) jantan galur Sprague dawley dalam jangka waktu 30 hari. Kata Kunci : minuman ringan berkarbonasi, kadar glukosa darah, diameter pulau Langerhans